     Calendar of EventsUpcoming EventsFriday, May 9, 2008 Tuan Ha-Ngoc, president and chief executive officer, is scheduled to present at the Leerink Swann Solid Tumors Roundtable Conference on at 10:20 a.m. (ET) at the Grand Hyatt in New York City. In addition, Murray Robinson, Ph.D., senior vice president, oncology, will participate in the conference’s expert panel discussion titled “Novel Targeted Agents for Cancer –What Target and Which Pathway?” at 8:35 a.m. (ET). Click here to view the presentation. Past Publications / Events American Association of Cancer Research San Diego, CA - April 12th – 16th, 2008 Poster Presentation by Dr. Joerg Heyer entitled, "Oncogene and tissue specific pathway activation in an HER2 dependent mouse mammary tumor model." Poster Presentation by Dr. Yinghui Zhou entitled, "Switching oncogene dependence in lung tumors in vivo." Poster Presentation by Dr. Lorena Lerner entitled, "Generation of in vivo tumor models driven by ERBB family of receptor tyrosine kinases and their use in cancer drug discovery." Poster Presenation by Dr. Karuppiah Kannan entitled, "Predicting rapamycin response using pathway profile in a population of genetically engineered hHER2 driven breast tumor model." Poster Presented by Dr. Karuppiah Kannan entitled, "Human cancer relevant genomic alterations in a population based genetically engineered murine model of human breast cancer." American Association of Cancer Research Los Angeles, CA - April 14th – 18th, 2007 Poster Presentation by Dr. Yinghui Zhou entitled, "A novel beta-Catenin dependent p53DN mouse model of colon cancer displays stage dependent expression of EGFR." Poster Presentation by Dr. Jie Lin entitled, "AV-412, a potent EGFR/HER2 TK inhibitor, causes tumor regression in novel genetically engineered EGFRL858R and EGFRL858R&T790M lung tumor models." Poster Presentation by Dr. Lorena Lerner entitled, "Directed Complementation of inducible tumor models: an approach to generate broad panels of tumors with defined genetic contexts." Poster Presentation by Dr. Yinghui Zhou entitled, "A chimeric mouse model of ovarian cancer driven by inducible expression of PI3K catalytic subunit (p110alpha)." Cancer Targets and Molecular Therapeutics (EORTC-NCI-AACR) American Association for Cancer Research (AACR) - Mouse Models of Cancer Poster presentation by Dr. Joerg Heyer from AVEO Pharmaceuticals entitled, "In-vivo Characterization of Major Pathways Implicated in Human Lung Cancer using Chimeric Lung Tumor Models". American Association for Cancer Research (AACR) Presentation by Dr. Tsuyoshi Suzuki from Mitsubishi Pharmaceuticals entitled, “MP-412, a dual EGFR/HER2 tyrosine kinase inhibitor shows antitumor activity against both Erlotinib/Gefitinib-sensitive and resistant EGFR mutations in human lung cancer xenograft models”. PublicationsPharmacological characterization of MP-412 (AV-412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor. Essential role for oncogenic Ras in tumour maintenance. |
|
 |
|
